Identification | Back Directory | [Name]
Pyrene -PEG4-acid | [CAS]
1817735-34-4 | [Synonyms]
Pyrene-PEG4-COOH Pyrene -PEG4-acid Pyrene-amido-PEG4-CH2CH2COOH Propanoic acid, 3-[[13-(4,6-dihydro-1-pyrenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]- | [Molecular Formula]
C28H33NO7 | [MDL Number]
MFCD29042349 | [MOL File]
1817735-34-4.mol | [Molecular Weight]
495.56 |
Chemical Properties | Back Directory | [Boiling point ]
744.5±60.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DMF, DCM | [pka]
4.28±0.10(Predicted) |
Hazard Information | Back Directory | [Description]
Pyrene-PEG-acid is a pyrene labeled PEG linker for the surface functionalization of carbon nanotube and graphene, graphene oxide, reduced graphene oxide. A strong pi-pi stacking is formed between the pyrene and the aromatic rings on single wall and multi-walled carbon nanotubes. | [Uses]
Pyrene-amido-PEG4-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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