| Identification | Back Directory | [Name]
Benzenesulfonamide, N-[3-(3-chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-N-methyl-4-(trifluoromethoxy)- | [CAS]
1810734-44-1 | [Synonyms]
TRC-766
Benzenesulfonamide, N-[3-(3-chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-N-methyl-4-(trifluoromethoxy)- | [Molecular Formula]
C25H24ClF3N2O3S | [MDL Number]
MFCD32857151 | [MOL File]
1810734-44-1.mol | [Molecular Weight]
524.98 |
| Chemical Properties | Back Directory | [Boiling point ]
597.0±60.0 °C(Predicted) | [density ]
1.341±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
0.83±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
TRC-766 is a negative control of RTC-5 (TRC-382). TRC-766 binds protein phosphatase 2A (PP2A) and does not activate the phosphatase[1]. | [References]
[1] Kimberly McClinch, et al. Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer. Cancer Res. 2018 Apr 15;78(8):2065-2080. DOI:10.1158/0008-5472.CAN-17-0123 |
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