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      ChemicalBook--->CAS DataBase List--->1808-12-4

      1808-12-4

      1808-12-4 Structure

      1808-12-4 Structure
      IdentificationBack Directory
      [Name]

      Bromazine Hydrochloride
      [CAS]

      1808-12-4
      [Synonyms]

      deserol
      bromazin
      Bromazine HCl
      bromo-benzdryl
      EINECS 204-238-8
      ambodrylhydrochloride
      bromazine hydrochloride
      Bromodiphenhydramine HCl
      bromodiphenhydraminehydrochloride
      Diphenhydramine EP Impurity C HCl
      bromdiphenylhydraminehydrochloride
      Diphenhydramine Impurity C hydrochloride
      Dimenhydrinate Impurity H as Hydrochloride
      Bromodiphenhydramine Hydrochloride (1077005)
      2-(4-bromodiphenylmethoxy)ethyldimethylamine
      Dimenhydrinate EP Impurity H as Hydrochloride
      BROMODIPHENHYDRAMINE HYDROCHLORIDE (200 MG)
      4-bromo-alpha-phenylbenzyl2-dimethylaminoethylether
      Diphenhydramine Impurity C HCl (Bromazine Hydrochloride)
      Diphenhydramine Impurity 3(Diphenhydramine EP Impurity C)
      Diphenhydramine Hydrochloride Impurity C as Hydrochloride
      2-(4-BroModiphenylMethoxy)ethyldiMethylaMine Hydrochloride
      2-(4-bromobenzohydryloxy)-ethyl-dimethylaminehydrochloride
      beta-(p-bromobenzhydryloxy)ethyldimethylaminehydrochloride
      Diphenhydramine Hydrochloride EP Impurity C as Hydrochloride
      2-[(4-bromophenyl)phenylmethoxy]ethyl(dimethyl)ammonium chloride
      2-((4-bromophenyl)phenylmethoxy)-n,n-dimethyl-ethanaminhydrochloride
      2-[(p-BroMo-α-phenylbenzyl)oxy]-N,N-diMethylethylaMine Hydrochloride
      2-[(4-BroMophenyl)phenylMethoxy]-N,N-diMethylethanaMine Hydrochloride
      2-((p-bromo-alpha-phenylbenzyl)oxy)-n,n-dimethylethylaminehydrochloride
      2-((p-bromo-alpha-phenylbenzyl)oxy)-n,n-dimethyl-ethylaminhydrochloride
      IMp. H (EP) as Hydrochloride: 2-[(RS)-(4- BroMophenyl)(phenyl)Methoxy]-N,N-diMethyl- ethanaMine Hydrochloride (4-BroModiphen- hydraMine Hydrochloride
      [EINECS(EC#)]

      217-310-9
      [Molecular Formula]

      C17H21BrClNO
      [MDL Number]

      MFCD01727165
      [MOL File]

      1808-12-4.mol
      [Molecular Weight]

      370.712
      Chemical PropertiesBack Directory
      [Melting point ]

      144-145°
      [storage temp. ]

      Refrigerator
      [solubility ]

      Acetone (Slightly), Methanol (Slightly), Water (Slightly)
      [form ]

      Solid
      [color ]

      Pale Yellow
      [BRN ]

      3754363
      Safety DataBack Directory
      [HS Code ]

      2922190900
      Hazard InformationBack Directory
      [Description]

      Bromodiphenhydramine is a histamine H1 receptor antagonist. It induces histamine release in isolated guinea pig lung when used at a concentration of 1 mM but completely prevents ovalbumin-induced histamine release in lungs isolated from ovalbumin-sensitized guinea pigs when used at concentrations of 100 and 200 μg/ml. Bromodiphenhydramine (17 mg/kg) inhibits formalin-induced paw edema in rats. It increases survival in a mouse model of systemic S. typhimurium infection when administered at doses of 1.5 and 3 mg/kg.
      [Uses]

      Antihistaminic.
      [Definition]

      ChEBI: The hydrochloride salt of bromazine. An antihistamine with antimicrobial properties, it is used in the control of cutaneous allergies.
      [Brand name]

      Ambodryl.
      [General Description]

      Bromodiphenhydraminehydrochloride, 2-[(4-bromophenyl)-phenylmethoxy]-N, N-dimethylethanamine hydrochloride(Ambodryl Hydrochloride), is a white to pale buff crystallinepowder that is freely soluble in water and in alcohol.Relative to diphenhydramine, bromodiphenhydramine ismore lipid soluble and was twice as effective in protectingagainst the lethal effects of histamine aerosols.
      Spectrum DetailBack Directory
      [Spectrum Detail]

      Bromazine Hydrochloride(1808-12-4)1HNMR
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