| Identification | Back Directory | [Name]
1-(2,4-bis (benzyloxy)-6-hydroxyphenyl) ethanone | [CAS]
18065-05-9 | [Synonyms]
2-Acetyl-3,5-bis(benzyloxy)phenol
1-(2,4-bis (benzyloxy)-6-hydroxyphenyl) ethanone
Ethanone, 1-[2-hydroxy-4,6-bis(phenylmethoxy)phenyl]- | [Molecular Formula]
C22H20O4 | [MOL File]
18065-05-9.mol | [Molecular Weight]
348.39 |
| Chemical Properties | Back Directory | [Melting point ]
108-109 °C(Solv: methanol (67-56-1)) | [Boiling point ]
550.4±45.0 °C(Predicted) | [density ]
1.206±0.06 g/cm3(Predicted) | [pka]
9.41±0.15(Predicted) |
| Hazard Information | Back Directory | [Uses]
1-(2,4-bis(Benzyloxy)-6-hydroxyphenyl)ethanone is a useful reactant for the synthesis of fluorine-containing chalcone derivatives that have antiproliferative activity. | [Preparation]
Preparation by reaction of benzyl chloride on phloroacetophenone with potassium carbonate in refluxing acetone (29%), (20%), in DMF at 100° (54%) and at 150–153° (26%) or in HMPA at 90–93° (80%). |
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