Identification | Back Directory | [Name]
OICR-0547 | [CAS]
1801873-49-3 | [Synonyms]
OICR-0547 3-Pyridinecarboxamide, 1,6-dihydro-N-[4-(4-morpholinyl)-3'-(4-morpholinylmethyl)[1,1'-biphenyl]-3-yl]-6-oxo-4-(trifluoromethyl)- | [Molecular Formula]
C28H29F3N4O4 | [MDL Number]
MFCD30533416 | [MOL File]
1801873-49-3.mol | [Molecular Weight]
542.55 |
Chemical Properties | Back Directory | [Boiling point ]
701.9±60.0 °C(Predicted) | [density ]
1.358±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 100 mg/mL (184.31 mM) | [form ]
Solid | [pka]
8.84±0.10(Predicted) | [color ]
Off-white to light yellow |
Hazard Information | Back Directory | [Uses]
OICR 0547, is a derivative of OICR-9429 (O249500), which is a chemical probe which inhibits the interaction of WDR5 (WD-repeat Protein 5) with peptide regions of MLL and Histone 3 with high selectivity. WDR5 is a part of the mixed-lineage leukemia (MLL) transferase complex that targets histone 3. | [Definition]
ChEBI: OICR-0547 is an aromatic amide. |
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InvivoChem
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Company Name: |
MedChemExpress
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021-58955995 |
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www.medchemexpress.com |
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