| Identification | Back Directory | [Name]
1400W | [CAS]
180001-34-7 | [Synonyms]
1400W
1400W DIHYDROCHLORIDE
N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE
N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL
N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE
N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE | [Molecular Formula]
C10H17Cl2N3 | [MDL Number]
MFCD03428622 | [MOL File]
180001-34-7.mol | [Molecular Weight]
250.17 |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
208-220 °C
| [Boiling point ]
301.7±44.0 °C(Predicted) | [density ]
1.09±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO, Methanol, Water | [form ]
solid
| [pka]
11.33±0.50(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM | [Biological Activity]
Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo . | [Definition]
ChEBI: N-[3-(aminomethyl)benzyl]acetamidine is an aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a geroprotector and an angiogenesis inhibitor. It is a carboxamidine, an aralkylamine and a primary amino compound. |
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