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ChemicalBook--->CAS DataBase List--->1799824-08-0

1799824-08-0

1799824-08-0 Structure

1799824-08-0 Structure
IdentificationBack Directory
[Name]

E-7386
[CAS]

1799824-08-0
[Synonyms]

E-7386,Epigenetic Reader Domain,E 7386,inhibit,Inhibitor
2H-Pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide, 8-[[6-[3-(4-ethyl-1-piperazinyl)-1-azetidinyl]-2-pyridinyl]methyl]-6-[(2-fluoro-4-hydroxyphenyl)methyl]hexahydro-4,7-dioxo-N-(phenylmethyl)-2-(2-propen-1-yl)-, (6S,9aS)-
[Molecular Formula]

C39H48FN9O4
[MOL File]

1799824-08-0.mol
[Molecular Weight]

725.85
Chemical PropertiesBack Directory
[density ]

1.39±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:125.0(Max Conc. mg/mL);172.21(Max Conc. mM)
[form ]

Solid
[pka]

8.92±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

E-7386, is an CBP/beta-catenin modulator that is shown to be orally active. E-7386, has shown high antitumor activity in Wnt1 model.
[storage]

Store at -20°C
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