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ChemicalBook--->CAS DataBase List--->179479-02-8

179479-02-8

179479-02-8 Structure

179479-02-8 Structure
IdentificationBack Directory
[Name]

N6-Bz-5'-O-DMTr-3'-O-methyladenosine-2'-O-CED-phosphoramidite
[CAS]

179479-02-8
[Synonyms]

3'-OMe-A(Bz) Phosphoramidite
3'-O-Me-A(Bz)-2'-phosphoramidite
N6-Bz-5'-O-DMTr-3'-O-methyladenosine-2'-O-CED-phosphoramidite
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'-CE-phosphoramidite
N6-Bz-5’-O-DMTr-3’-O-methyladenosine-2’-O-CED-phosphoramidite,3’-O-Me-A(Bz)-2’-phosphoramidite
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
[Molecular Formula]

C48H54N7O8P
[MDL Number]

MFCD30475579
[MOL File]

179479-02-8.mol
[Molecular Weight]

887.97
Chemical PropertiesBack Directory
[pka]

7.87±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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