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ChemicalBook--->CAS DataBase List--->179258-62-9

179258-62-9

179258-62-9 Structure

179258-62-9 Structure
IdentificationBack Directory
[Name]

Benzamide, N-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-4-nitro-, hydrochloride (1:1)
[CAS]

179258-62-9
[Synonyms]

SB237376
SB-237376
SB 237376
SB-237376 HCl
SB-237376 hydrochloride
SB237376 HCl,SB 237376 HCl
Benzamide, N-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-4-nitro-, hydrochloride (1:1)
[Molecular Formula]

C20H26ClN3O5
[MDL Number]

MFCD00947905
[MOL File]

179258-62-9.mol
[Molecular Weight]

423.89
Hazard InformationBack Directory
[Uses]

SB-237376 is a blocker of potassium and calcium channels. SB-237376 inhibits the rapidly activating delayed rectifier potassium current I(Kr) (IC50: 0.42 μM) and blocks the L-type calcium current I(Ca,L) at high concentrations[1].
[References]

[1] Xu X, et al. Electrophysiologic effects of SB-237376: a new antiarrhythmic compound with dual potassium and calcium channel blocking action. J Cardiovasc Pharmacol. 2003 Mar;41(3):414-21. DOI:10.1097/00005344-200303000-00010
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