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ChemicalBook--->CAS DataBase List--->17618-08-5

17618-08-5

17618-08-5 Structure

17618-08-5 Structure
IdentificationBack Directory
[Name]

1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT)
[CAS]

17618-08-5
[Synonyms]

16:0 LPA
16:0 Lyso PA
PA(16:0/0:0)
16:0 LYSO PA SODIUM SALT
1-Palmitoyl Lysophosphatidic acid Sodium
1-Palmitoyl-lyso-Phosphatidic acid Na salt
Sodium (R)-2-hydroxy-3-(palmitoyloxy)propyl phosphate
1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT)
1-Palmitoyl Lysophosphatidic Acid (sodium salt) Exclusive
1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE (SODIUM SALT);16:0 LYSO PA;16:0 LPA;PA(16:0/0:0)
[Molecular Formula]

C19H37Na2O7P
[MDL Number]

MFCD00674362
[MOL File]

17618-08-5.mol
[Molecular Weight]

454.45
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: <.05 mg/ml; DMSO: <.05 mg/ml; Ethanol: <.05 mg/ml
[form ]

A crystalline solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. In addition to playing a role in the aforementioned biological responses, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of Pseudomonas aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.
[Uses]

(2R)-2-Hydroxy-3-(phosphonooxy)propyl hexadecanoate Sodium Salt is used in the test kit for screening colorectal adenoma.
[storage]

Store at -20°C
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