Identification | Back Directory | [Name]
DILAURIN | [CAS]
17598-94-6 | [Synonyms]
DILAURIN Diglyceride DIDODECANOIN 1,2-DILAURIN DILAURIN (C12:0) glyceryl 1,2-dilaurate 1,3-dilaurate glycerol 1,2-didodecanoylglycerol 1,2,3-Propanetriol 1,2-didodecanoate Dilauric acid 3-hydroxy-1,2-propanediyl ester Didodecanoic acid 3-hydroxy-1,2-propanediyl ester Dodecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester | [Molecular Formula]
C27H52O5 | [MDL Number]
MFCD00048420 | [MOL File]
17598-94-6.mol | [Molecular Weight]
456.7 |
Chemical Properties | Back Directory | [Melting point ]
53-56 °C | [Boiling point ]
531.0±17.0 °C(Predicted) | [density ]
0.953±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [form ]
A crystalline solid | [pka]
13.69±0.10(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981). | [References]
[1] Zhu X, et al. 1,2-diacylglycerol content and its arachidonyl-containing molecular species are reduced in sciatic nerve from streptozotocin-induced diabetic rats. J Neurochem. 1990 Sep;55(3):1087-90. DOI:10.1111/j.1471-4159.1990.tb04604.x [2] Wieloch T, et al. Porcine pancreatic procolipase and its trypsin-activated form: lipid binding and lipase activation on monomolecular films. FEBS Lett. 1981 Jun 15;128(2):217-20. DOI:10.1016/0014-5793(81)80084-1 |
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