| Identification | Back Directory | [Name]
Benzeneethanol, beta-amino-4-fluoro-, (betaR)- (9CI) | [CAS]
174770-74-2 | [Synonyms]
(R)-b-AMino-4-fluoro-benzeneethanol
(R)-2-AMino-2-(4-fluorophenyl)ethanol
(2R)-2-amino-2-(4-fluorophenyl)ethanol
(R)-2-Amino-2-(4-fluorophenyl)ethan-1-ol
Benzeneethanol, β-amino-4-fluoro-, (βR)-
(R)-2-AMINO-2-(4-FLUOROPHENYL)ETHANOL HCL
(2R)-2-AMINO-2-(4-FLUOROPHENYL)ETHAN-1-OL
Benzeneethanol, beta-aMino-4-fluoro-, (betaR)-
Benzeneethanol, beta-amino-4-fluoro-, (betaR)- (9CI) | [Molecular Formula]
C8H10FNO | [MDL Number]
MFCD09253715 | [MOL File]
174770-74-2.mol | [Molecular Weight]
155.17 |
| Chemical Properties | Back Directory | [Boiling point ]
287.4±25.0 °C(Predicted) | [density ]
1.208±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [pka]
12.48±0.10(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
(R)-2-Amino-2-(4-fluorophenyl)ethanol is a white solid. | [Uses]
(R)-2-Amino-2-(4-fluorophenyl)ethanol is used for synthesis of organic compounds. | [Hazard]
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation. | [Synthesis]
To a stirred solution of lithium aluminium hydride (1.0 M in THF, 11.9 ml, 11.9 mmol) at 0℃ was added 4- (R)-fluorophenylglycine (1.0 g, 5.9 mmol) portion wise over 1 hour. The mixture was stirred at room temperature for 16 hours. Water (0.45 ml), 4 NNaOH (0.45 ml) and water (1.34 ml) was added to the mixture and the mixture was stirred for 10 minutes before being filtered. The filtrate was concentrated to give a yellow residue, (R)-2-Amino-2-(4-fluorophenyl)ethanol. |
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NovoChemy Ltd.
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