| Identification | Back Directory | [Name]
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe | [CAS]
17302-61-3 | [Synonyms]
1-oxime
PoloxiMe
5-Cyclohexadiene-1
2-methyl-5-(1-methylethyl)-
p-Mentha-3,6-diene-2,5-dione 2-oxime
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe | [Molecular Formula]
C10H13NO2 | [MDL Number]
MFCD22572808 | [MOL File]
17302-61-3.mol | [Molecular Weight]
179.22 |
| Chemical Properties | Back Directory | [Melting point ]
162℃ (Decomposition) | [Boiling point ]
296.8±33.0 °C(Predicted) | [density ]
1.10±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Powder | [pka]
6.43±0.58(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
Poloxime is a hydrolysis product of poloxin, a non-competitive ATP inhibitor of Plk1, which can properly inhibit the activity of Plk1. | [in vitro]
Poloxime (100 μM) inhibits phosphopeptide binding to polo-box domain (PBD) of polo-like kinase 1 (Plk1). | [target]
| [storage]
Store at -20°C |
|
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