| Identification | Back Directory | [Name]
FGFR4-IN-1 | [CAS]
1708971-72-5 | [Synonyms]
CS-2343
FGFR4-IN-1
FGFR4 inhibitor 1
N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(3-oxomorpholin-4-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(3-oxo-4-morpholinyl)methyl]- | [Molecular Formula]
C24H27N7O5 | [MDL Number]
MFCD30489746 | [MOL File]
1708971-72-5.mol | [Molecular Weight]
493.52 |
| Chemical Properties | Back Directory | [Boiling point ]
875.4±65.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Chloroform: 30 mg/ml; DMSO: *1 mg/ml | [form ]
A crystalline solid | [pka]
11.39±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC50 of 0.7 nM. | [IC 50]
FGFR4: 0.7 nM (IC50) | [References]
[1] Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors. WO 2015059668 A1? |
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
|