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ChemicalBook--->CAS DataBase List--->1673516-98-7

1673516-98-7

1673516-98-7 Structure

1673516-98-7 Structure
IdentificationBack Directory
[Name]

Relatlimab
[CAS]

1673516-98-7
[Synonyms]

ONO-4482
BMS986016
BMS-986016
Relatlimab
Relatlimab (DHD30403)
Relatlimab (anti-LAG-3/CD223)
Research Grade Relatlimab(DHD30403)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer[1].
[References]

[1] Thudium K, et, al. Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab. Cancer Immunol Res. 2022 Aug 18:CIR-22-0057. DOI:10.1158/2326-6066.CIR-22-0057
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