| Identification | Back Directory | [Name]
beta-D-Glucopyranoside 3-[(1Z)-2-[4-(beta-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl | [CAS]
166734-06-1 | [Synonyms]
cis-Mulberroside A
beta-D-Glucopyranoside 3-[(1Z)-2-[4-(beta-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl | [Molecular Formula]
C26H32O14 | [MDL Number]
MFCD17167012 | [MOL File]
166734-06-1.mol | [Molecular Weight]
568.524 |
| Hazard Information | Back Directory | [Uses]
Cis-Mulberroside A is an impurity of Mulberroside A is a stilbenoid found in Morus alba plants. Potential metabolite for Oxyresveratrol (O861920), a natural hydroxystilbene with similar bioactivity to resveratrol. COX-1 inhibitor like resveratrol (R150000), anti-cancer agent. | [in vivo]
Mulberroside A (10, 20, and 40 mg/kg) decreases serum uric acid levels and increases urinary urate excretion and fractional excretion of uric acid in hyperuricemic mice[4]. | Animal Model: | Male Kun-Ming mice (20±2 g)[4] | | Dosage: | 5, 10, 20, and 40 mg/kg; the dose volume 10 mL/kg body weight | | Administration: | Orally initiated at 9:00 a.m. | | Result: | 10, 20, and 40 mg/kg significantly increased urinary urate excretion in 24 h, resulting in a remarkable elevation of fractional excretion of uric acid (FEUA), and the highest dose completely reversed FEUA alteration of hyperuricemic mice to normal. |
| [IC 50]
IL-6; IL-1β |
|
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
www.biorbyt.com |
|