| Identification | Back Directory | [Name]
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER | [CAS]
16600-22-9 | [Synonyms]
NSC 403048
3-Carbethoxy-4-hydroxy-7-chloroquinoline
Ethyl7-chloro-4-hydroxy-3-quinolinecarboxylate
Ethyl 4-hydroxy-7-chloroquinoline-3-carboxylate
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate
ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate
Ethyl-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylate
4-Hydroxy-7-chloroquinoline-3-carboxylic acid ethyl ester
7-chloro-4-oxo-1H-quinoline-3-carboxylic acid methyl ester
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, ethyl ester | [Molecular Formula]
C12H10ClNO3 | [MDL Number]
MFCD00438741 | [MOL File]
16600-22-9.mol | [Molecular Weight]
251.67 |
| Chemical Properties | Back Directory | [Melting point ]
296-298℃ | [Boiling point ]
366.8±37.0 °C(Predicted) | [density ]
1.386 | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
2.18±0.50(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline compounds. Melting point 297 ℃. | [Uses]
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be used as an intermediate of chloroquine. | [Synthesis]
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be obtained by heating and condensing m-chloroaniline and triethyl orthoformate, then condensing with diethyl malonate with the participation of boron trifluoride, and finally heating and cyclizing in paraffin oil. |
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SynAsst Chemical.
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Energy Chemical
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http://www.energy-chemical.com |
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