| Identification | Back Directory | [Name]
EOS-62353 | [CAS]
1657014-42-0 | [Synonyms]
EOS-62353
GDC-0575 2HCl
GDC-0575 dihydrochloride | [Molecular Formula]
C16H21BrClN5O | [MDL Number]
MFCD31692377 | [MOL File]
1657014-42-0.mol | [Molecular Weight]
414.73 |
| Hazard Information | Back Directory | [Description]
GDC-0575, also known as ARRY-575 and RG7741, is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. Chk1 inhibitor GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis. |
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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