| Chemical Properties | Back Directory | [Boiling point ]
792.7±60.0 °C(Predicted) | [density ]
1.201±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.11±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
SCO-267 is a novel GPR40 full agonist, improving liver parameters in a mouse model of nonalcoholic fatty liver disease without affecting glucose or body weight. | [Uses]
SCO-267 is an allosteric GPR40 full agonist. SCO-267 can be used for the research of chronic diseases including diabetes[1]. | [in vivo]
SCO-267 (1 or 10 mg/kg; p.o.) improves insulin sensitivity and exerts sustained glucose-lowering effect[1]. | Animal Model: | N-STZ rats[1] | | Dosage: | 1 or 10 mg/kg | | Administration: | P.o.; | | Result: | Improved insulin sensitivity and exerted sustained glucose-lowering effect.
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| [References]
[1] Koyama R, et al. Chronic Exposure to SCO-267, an Allosteric GPR40 Full Agonist, Is Effective in Improving Glycemic Control in Rats. Mol Pharmacol. 2021 Apr;99(4):286-293. DOI:10.1124/molpharm.120.000168 |
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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http://m.is0513.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Unibest Pharmaceutical Technology Co., Ltd.
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13735578103 |
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| Company Name: |
mahaloong
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+86-028-81192082 +86-18180560816 |
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https://www.mahaloong.com |
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Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Website: |
www.biorbyt.com |
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