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ChemicalBook--->CAS DataBase List--->165454-06-8

165454-06-8

165454-06-8 Structure

165454-06-8 Structure
IdentificationBack Directory
[Name]

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA
[CAS]

165454-06-8
[Synonyms]

CBZ-AEEA
CBZ-AEEA.DCHA
Cb-NH-PEG2-CH2COOH
CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA
2-[2-(Cbz-amino)ethoxy]ethoxyacetic acid
8-Benzyloxycarbonylamino-3,6-dioxaoctanoic acid
3,6,11-Trioxa-9-azadodecanoic acid, 10-oxo-12-phenyl-
3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oic acid
[Molecular Formula]

C14H19NO6
[MDL Number]

MFCD23379879
[MOL File]

165454-06-8.mol
[Molecular Weight]

297.3
Chemical PropertiesBack Directory
[Boiling point ]

506.6±45.0 °C(Predicted)
[density ]

1.233±0.06 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[form ]

Viscous Liquid
[pka]

3.40±0.10(Predicted)
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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