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ChemicalBook--->CAS DataBase List--->1642839-27-7

1642839-27-7

1642839-27-7 Structure

1642839-27-7 Structure
IdentificationBack Directory
[Name]

1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)-
[CAS]

1642839-27-7
[Synonyms]

GRK5-IN-2
1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)-
[Molecular Formula]

C20H20N4O4
[MDL Number]

MFCD34470578
[MOL File]

1642839-27-7.mol
[Molecular Weight]

380.4
Chemical PropertiesBack Directory
[Boiling point ]

561.1±60.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 83.33 mg/mL (219.06 mM; Need ultrasonic)
[form ]

Solid
[pka]

5.61±0.50(Predicted)
[color ]

Light yellow to brown
Hazard InformationBack Directory
[Biological Activity]

GRK5-IN-2 (compound 707), a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. GRK5-IN-2 regulates the expression and/or release of insulin and is useful for the metabolic disease research[1].
[References]

[1]. Axel Ullrich (Prof. Dr.), et al. Imidazo[4,5-c]pyridine and pyrrolo[3,2-c]pyridine compounds as G-protein-coupled receptor kinase 5 (GRK5) modulators. EP2818472A1.
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