Identification | Back Directory | [Name]
2-Methoxy-4-(3-methyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenol | [CAS]
1638211-04-7 | [Synonyms]
ML303 2-Methoxy-4-(3-methyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenol | [Molecular Formula]
C21H16F3N3O2 | [MDL Number]
MFCD28168046 | [MOL File]
1638211-04-7.mol | [Molecular Weight]
399.37 |
Chemical Properties | Back Directory | [Boiling point ]
483.6±45.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 20mg/mL, clear | [form ]
powder | [pka]
8.01±0.20(Predicted) | [color ]
white to beige |
Hazard Information | Back Directory | [Biological Activity]
It belongs to the pyrazolopyridine family.''ML303 is a potent inhibitor (IC50 = 155 nM) of the influenza viral protien NS1. NS1 enhances virulence by inhibiting host cell immune responsesincluding the expression of IFN-band regulating synthesissplicing and translation of viral RNA. |
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