| Identification | Back Directory | [Name]
Auristatin F | [CAS]
163768-50-1 | [Synonyms]
CS-1370
Auristatin F
Auristantin F
Auristatin F （AF）
Auristatin F TFA Salt
L-Phenylalanine, N,N-dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-
N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide | [Molecular Formula]
C40H67N5O8 | [MDL Number]
MFCD25976745 | [MOL File]
163768-50-1.mol | [Molecular Weight]
746 |
| Chemical Properties | Back Directory | [Melting point ]
>140°C (dec.) | [Boiling point ]
894.4±65.0 °C(Predicted) | [density ]
1.112±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
3.56±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
Auristatin F is a cytotoxin that works as a microtubule inhibitor and vascular damaging agent. | [Uses]
Auristatin F is an antimitotic auristatin derivative that has been shown as a potent antitumor agent. |
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