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ChemicalBook--->CAS DataBase List--->1630086-20-2

1630086-20-2

1630086-20-2 Structure

1630086-20-2 Structure
IdentificationBack Directory
[Name]

Amgen IRE1α Inhibitor
[CAS]

1630086-20-2
[Synonyms]

Kira8
KIRA8 (AMG-18)
IRE-1 INHIBITOR
Amgen IRE1α Inhibitor
Benzenesulfonamide, 2-chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]-
[Molecular Formula]

C31H29ClN6O3S
[MDL Number]

MFCD28404657
[MOL File]

1630086-20-2.mol
[Molecular Weight]

601.12
Chemical PropertiesBack Directory
[Boiling point ]

812.6±75.0 °C(Predicted)
[density ]

1.383±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Water:30.0(Max Conc. mg/mL);49.91(Max Conc. mM)
[form ]

Solid
[pka]

7.66±0.30(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Amgen IRE1α Inhibitor is an inhibitor of IRE1α. IRE1α is a sensor of unfolded protein accumulation that triggers the unfolded protein response.
Spectrum DetailBack Directory
[Spectrum Detail]

Amgen IRE1α Inhibitor(1630086-20-2)1HNMR
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