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ChemicalBook--->CAS DataBase List--->1621002-23-0

1621002-23-0

1621002-23-0 Structure

1621002-23-0 Structure
IdentificationBack Directory
[Name]

PF-6422899 >=98% (HPLC)
[CAS]

1621002-23-0
[Synonyms]

PF-6422899 >=98% (HPLC)
[Molecular Formula]

C20H14ClFN4O2
[MDL Number]

MFCD28386019
[MOL File]

1621002-23-0.mol
[Molecular Weight]

396.8
Chemical PropertiesBack Directory
[Boiling point ]

612.0±55.0 °C(Predicted)
[density ]

1.429±0.06 g/cm3(Predicted)
[storage temp. ]

room temp
[solubility ]

DMSO: 5mg/mL, clear (warmed)
[form ]

powder
[pka]

11.83±0.43(Predicted)
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard InformationBack Directory
[Description]

PF-6422899 is an irreversible inhibitor of EGFR kinase activity. PF-6422899 binds covalently to active-site cysteine residues in the ATP binding pocket of EGFR.
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