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ChemicalBook--->CAS DataBase List--->1620846-16-3

1620846-16-3

1620846-16-3 Structure

1620846-16-3 Structure
IdentificationBack Directory
[Name]

2-(4-fluoro-2-methylphenoxy)-N-(2-oxo-1l4,2l5-pyridin-4-yl)-4-(trifluoromethyl)benzamide
[CAS]

1620846-16-3
[Synonyms]

EOS-62075
Nav1.8-IN-4
2-(4-fluoro-2-methylphenoxy)-N-(2-oxo-1l4,2l5-pyridin-4-yl)-4-(trifluoromethyl)benzamide
2-(4-Fluoro-2-methylphenoxy)-N-(2-oxo-1,2-dihydropyridin-4-yl)-4-(trifluoromethyl)benzamide
Benzamide, N-(1,2-dihydro-2-oxo-4-pyridinyl)-2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)-
[Molecular Formula]

C20H14F4N2O3
[MDL Number]

MFCD31803782
[MOL File]

1620846-16-3.mol
[Molecular Weight]

406.33
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Nav1.8-IN-4 (compound 9a) is a Nav1.8 channel inhibitor (IC50=0.014 μM). Nav1.8-IN-4 can be used for research on pain-related diseases[1].
[References]

[1] Corey Anderson, et al. Prodrugs of pyridone amides useful as modulators of sodium channels. Patent WO2015089361A1.
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