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6-O-Methylcatalpol can be isolated from the roots of Scrophularia ningpoensis. 6-O-Methylcatalpol has anti-protozoal activity against Trypanosoma b. rhodesiense and Leishmania donovani (IC50: 32.5 and 8.3 μg/mL)[1][2]. | [References]
[1] Niu ZR, et al. A new iridoid glycoside from Scrophularia ningpoensis. Nat Prod Res. 2009;23(13):1181-8. DOI:10.1080/14786410802386344
[2] Tasdemir D, et al. Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots. Phytochemistry. 2005 Feb;66(3):355-62. DOI:10.1016/j.phytochem.2004.11.013 |
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