成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook--->CAS DataBase List--->1609583-14-3

1609583-14-3

1609583-14-3 Structure

1609583-14-3 Structure
IdentificationBack Directory
[Name]

PF-06256142
[CAS]

1609583-14-3
[Synonyms]

PF-06256142
[Molecular Formula]

C21H16N4O2
[MOL File]

1609583-14-3.mol
[Molecular Weight]

356.38
Chemical PropertiesBack Directory
[density ]

1.34±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 200 mg/mL (514.88 mM; Need ultrasonic)
[form ]

Solid
[pka]

4.68±0.40(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

PF-06256142 is a potent, selective, CNS-penetrant and orally active agonist of the D1 receptor, with an EC50 and Ki of 33 nM and 12 nM, respectively. PF-06256142 has the potential for the research of schizophrenia and Parkinson's disease[1]. PF-06256142 exhibits IC50 values of 10 μM)[1]. PF-06256142 exhibits high oral bioavailability (rat 85%) following oral administration (rat 5 mg/kg)[1].PF-06256142 exhibits terminal elimination half-life (rat 2.3 h) following intravenous administration (rat 5.0 mg/kg)[1].
[References]

[1]. Davoren JE, et al. Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization. J Med Chem. 2018 Nov 15.
1609583-14-3 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: TargetMol Chemicals Inc.
Tel:
Website: www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135 , +8613564774135
Website:
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185 18149758185
Website: www.caerulumpharma.com
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
Tel: 010-50973130 4009686088
Website: http://www.solarbio.com
Company Name: DC Chemicals  
Tel: 021-58447131 13564518121
Website: http://m.is0513.com/ShowSupplierProductsList927327/0.htm
Company Name: InvivoChem  
Tel: 13549236410
Website: https://www.invivochem.cn/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Tags:1609583-14-3 Related Product Information