Chemical Properties | Back Directory | [Boiling point ]
519.3±50.0 °C(Predicted) | [density ]
1.277±0.06 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
DMSO: 30mg/mL, clear | [form ]
powder | [pka]
11.41±0.40(Predicted) | [color ]
white to beige |
Hazard Information | Back Directory | [Description]
PF2562 is a non-catechol dopamine 1 receptor agonist. Dopamine D1 receptors are implicated in numerous neuropharmacological and neurobiological functions. For example, D1 receptors are involved in different types of memory function and synaptic plasticity. | [Uses]
PF2562 (Example 6), a dopamine D1 ligand, ascts as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor with a Ki of 113 nM. PF2562 exhibits activity against human D1 cAMP with an EC50 of 568 nM in HTRF assay[1]. | [References]
[1] Jennifer Elizabeth Davoren, et al. Heteroaromatic compounds and their use as dopamine d1 ligands. US20140128374A1. |
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Energy Chemical
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cjbscvictory
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mahaloong
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Merck KGaA
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