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ChemicalBook--->CAS DataBase List--->1599440-14-8

1599440-14-8

1599440-14-8 Structure

1599440-14-8 Structure
IdentificationBack Directory
[Name]

L-Phenylalanine, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-, 1,1-dimethylethyl ester
[CAS]

1599440-14-8
[Synonyms]

MC-Gly-Gly-Phe-Boc
N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]
L-Phenylalanine, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-, 1,1-dimethylethyl ester
[Molecular Formula]

C27H36N4O7
[MOL File]

1599440-14-8.mol
[Molecular Weight]

528.6
Chemical PropertiesBack Directory
[Boiling point ]

820.2±65.0 °C(Predicted)
[density ]

1.218±0.06 g/cm3(Predicted)
[pka]

13.21±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

MC-Gly-Gly-Phe-Boc is involved in the synthesis of antibody-drug conjugates (ADCs) to Trastuzumab (HY-P9907). MC-Gly-Gly-Phe-Boc can participate in cancer research[1].
[References]

[1] Naito Hiroyuki, et al. Anti-human HER2 antibody drug conjugates with excellent safety and therapeutic antitumor effect: World Intellectual Property Organization, WO2015115091 A1 2015-08-06.
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