| Identification | Back Directory | [Name]
PARAMETHASONE ACETATE (200 MG) | [CAS]
1597-82-6 | [Synonyms]
dilar
Dillar
Stemex
C12656
Metilar
alondra
haldrate
haldrone
cortidene
Syntecort
Sintecort
Paramezone
Flumethone
21-Acetate
monocortin
Haldrone (TN)
paramethasoneacetate
paramethasone21-acetate
PARAMETHASONE ACETATE (200 MG)
Paramethasone acetate Solution, 100ppm
21-Acetyl-6a-fluoro-16a-methylprednisolone
16a-Methyl-6a-fluoroprednisolone 21-acetate
6a-Fluoro-16a-methylprednisolone 21-acetate
21-acetyl-6-alpha-fluoro-16-alpha-methylprednisolone
6-alpha-fluoro-16-alpha-methylprednisolone21-acetate
16-alpha-methyl-6-alpha-fluoro-prednisolone-21-acetate
21-Acetoxy-6a-fluoro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione
pregna-1,4-diene-3,20-dione,6-alpha-fluoro-11-beta,17,21-trihydroxy-16-alpha-m
6a-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-acetate
Pregna-1,4-diene-3,20-dione, 6a-fluoro-11b,17,21-trihydroxy-16a-methyl-, 21-acetate (6CI, 7CI, 8CI)
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6-fluoro-11,17-dihydroxy-16-methyl-, (6a,11b,16a)- (9CI) | [EINECS(EC#)]
216-486-4 | [Molecular Formula]
C24H31FO6 | [MDL Number]
MFCD00200359 | [MOL File]
1597-82-6.mol | [Molecular Weight]
434.498 |
| Chemical Properties | Back Directory | [Melting point ]
228-241° (dec) | [alpha ]
D +85° | [Boiling point ]
584.2±50.0 °C(Predicted) | [density ]
1.1517 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.29±0.70(Predicted) | [color ]
Crystals from Me2CO/hexane | [EPA Substance Registry System]
Paramethasone acetate (1597-82-6) |
| Hazard Information | Back Directory | [Originator]
Haldrone,Lilly,US,1961 | [Uses]
Glucocorticoid. | [Uses]
Paramethasone Acetate, is a derivative of Dexamethasone (D298800), a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties. | [Definition]
ChEBI: Paramethasone acetate is a corticosteroid hormone. | [Manufacturing Process]
A solution of 0.144 g of the 3-ethylene glycol ketal of 5α,11β,17α,21 tetrahydroxy-6β-fluoro-16α-methylallopregnane-3,20-dione-21 acetate in 12 ml of chloroform and 0.1 ml of absolute alcohol was cooled to -10°C in an icesalt bath and a stream of anhydrous hydrochloric acid was gently bubbled through the solution for 2.5 hours while the temperature was maintained between -5°C and -15°C. The solution was then diluted with 25 ml of chloroform, washed with dilute sodium bicarbonate and water, dried over anhydrous sodium sulfate, and evaporated to dryness under reduced pressure at 60°C or less to give 6α-fluoro-11β,17α,21-trihydroxy-16α-methyl-4-pregnene3,20-dione 21-acetate.
| [Brand name]
Haldrone (Lilly). | [Therapeutic Function]
Glucocorticoid | [Safety Profile]
Poison by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits toxic fumes of Fí. |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
ChemCell Biomedicine Co.,Ltd.
|
| Tel: |
020-13556033878 2965585218 13556033878 |
| Website: |
http://m.is0513.com/ShowSupplierProductsList15061/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|