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ChemicalBook--->CAS DataBase List--->159351-88-9

159351-88-9

159351-88-9 Structure

159351-88-9 Structure
IdentificationBack Directory
[Name]

28-O-Methyl-rapaMycin
[CAS]

159351-88-9
[Synonyms]

28-O-Methyl-rapaMycin
Rapamycin Impurity 13
[Molecular Formula]

C52H81NO13
[MOL File]

159351-88-9.mol
[Molecular Weight]

928.21
Chemical PropertiesBack Directory
[Melting point ]

>102°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

28-O-Methyl-rapamycin is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
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