| Identification | Back Directory | [Name]
2,3-Dihydro-3-methyl-1,2,6,7-tetrahydroxy-1H-benzo(a)fluorene-4,11-dio ne | [CAS]
158906-40-2 | [Synonyms]
2,3-Dihydro-3-methyl-1,2,6,7-tetrahydroxy-1H-benzo(a)fluorene-4,11-dio ne
1H-Benzo[a]fluorene-4,11-dione, 2,3-dihydro-1,2,6,7-tetrahydroxy-3-methyl- (9CI) | [Molecular Formula]
C18H14O6 | [MDL Number]
MFCD00940459 | [MOL File]
158906-40-2.mol | [Molecular Weight]
326.3 |
| Hazard Information | Back Directory | [Description]
Fluostatin B is a fluorenone originally found in Streptomyces.1 It inhibits dipeptidyl peptidase 3 (DPP-3; IC50 = 24 μg/ml). | [Uses]
Fluostatin B is a dipeptidyl peptidase 3 (DPP-3) inhibitor with an IC50 value of 24 μg/mL. Fluostatin B is a fluorenone, which is found in Streptomyces[1]. | [References]
1. Akiyama, T., Harada, S., Kojima, F., et al. Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. I. Taxonomy of producing strain, production, isolation, physico-chemical properties and biological properties J. Antibiot. (Tokyo) 51(6),553-559(1998). |
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