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ChemicalBook--->CAS DataBase List--->157230-67-6

157230-67-6

157230-67-6 Structure

157230-67-6 Structure
IdentificationBack Directory
[Name]

DEPMPO
[CAS]

157230-67-6
[Synonyms]

DEPMPO
5-(Diethoxyphosphoryl)-
5-(DIETHYLPHOSPHONO)-5-METHYL-1-PYRROLINE N-OXIDE
5-(DIETHOXYPHOSPHONYL)-5-METHYL-1-PYRROLINE-N-OXIDE
5-(DIETHOXYPHOSPHORYL)-5-METHYL-1-PYRROLINE-N-OXIDE
5-(Diethylphosphono)-5-methyl-1-pyrroline N-Oxide
2-DIETHYLPHOSPHONO-2-METHYL-3,4-DIHYDRO-2H-PYRROLE 1-OXIDE
(2-METHYL-3,4-DIHYDRO-1-OXIDE-2H-PYRROL-2-YL)DIETHYLPHOSPHONATE
(3,4-Dihydro-2-methyl-1-oxido-2H-pyrrol-2-yl)-phosphonic acid diethyl ester
P-(3,4-Dihydro-2-Methyl-1-oxido-2H-pyrrol-2-yl)phosphonic Acid Diethyl Ester
[Molecular Formula]

C9H18NO4P
[MDL Number]

MFCD01074976
[MOL File]

157230-67-6.mol
[Molecular Weight]

235.22
Chemical PropertiesBack Directory
[Appearance]

Pale Yellow Oil
[Boiling point ]

412.4±34.0 °C(Predicted)
[density ]

1.14±0.1 g/cm3(Predicted)
[storage temp. ]

Freezer
[solubility ]

Soluble in Water or Ethanol.
[form ]

Colorless to light yellow oil.
[pka]

1.74±0.40(Predicted)
[color ]

Pale yellow
[Stability:]

Hygroscopic Oil, Light Sensitive
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Oil
[Uses]

A spin trap useful as a probe for free radical formation during myocardial ischemia/reperfusion injury. An analogue of DMPO
[Description]

DEPMPO (157230-67-6) is a spin trap capable of detecting oxygen, nitrogen, sulfur and carbon-centered free radicals both in vitro and in vivo. DEPMPO is useful for distinguishing between superoxide-dependent pathways of hydroxyl radical generation, and those that are superoxide independent.
[storage]

Store at -80°C,protect from light
[References]

1) Liu et al. (1999), Evaluation of DEPMPO as a spin trapping agent in biological systems; Free Radic. Biol. Med., 26 714 2) Shi et al. (2005), Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species; Arch. Biochem. Biophys., 437 59 3) Culcasi et al. (2012), EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: evidence for NADPH oxidase and mitochondrial stimulation; Chem. Biol. Interact., 199 161 4) Tampieri et al. (2019), Comment on “Water Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos; ACS Sens. E-pub. Ahead of Print [Focus Citation]
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