| Identification | Back Directory | [Name]
5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE | [CAS]
157066-76-7 | [Synonyms]
SNAP 5089
3-Pyridinecarboxylic acid, 5-[[[3-(4,4-diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-, methyl ester
5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE | [Molecular Formula]
C36H40N4O5 | [MDL Number]
MFCD09971074 | [MOL File]
157066-76-7.mol | [Molecular Weight]
608.73 |
| Chemical Properties | Back Directory | [Boiling point ]
780.3±60.0 °C(Predicted) | [density ]
1.198±0.06 g/cm3(Predicted) | [storage temp. ]
Store at +4°C | [solubility ]
<64.52mg/ml in DMSO; <64.52mg/ml in ethanol | [pka]
14.77±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
SNAP 5089 is an a1c adrenergic receptor antagonist. | [Biological Activity]
Subtype-selective α 1A -adrenoceptor antagonist that displays > 600-fold selectivity over other adrenoceptors (K i values are 0.35, 220, 370, 540, 800 and 1200 nM for α 1A , α 1B , α 2C , α 1D , α 2B and α 2A subtypes respectively and 540 nM for L-type Ca 2+ channels). Inhibits noradrenalin-induced contractions in rabbit vascular and lower urinary tissues. | [storage]
Store at -20°C |
|
| Company Name: |
|
| Tel: |
821-50328103-801 18930552037 |
| Website: |
http://m.is0513.com/ShowSupplierProductsList13285/0.htm |
|