Identification | Back Directory | [Name]
Alisol F | [CAS]
155521-45-2 | [Synonyms]
Alisol F Dammar-13(17)-en-3-one,16,23-epoxy-11,24,25-trihydroxy-, (8a,9b,11b,14b,16b,23S,24R)- Dammar-13(17)-en-3-one, 16,23-epoxy-11,24,25-trihydroxy-, (8α,9β,11β,14β,16β,23S,24R)- (8alpha,9beta,11beta,14beta,16beta,23S,24R)-16,23-Epoxy-11,24,25-trihydroxydammar-13(17)-en-3-one | [Molecular Formula]
C30H48O5 | [MDL Number]
MFCD28411505 | [MOL File]
155521-45-2.mol | [Molecular Weight]
488.71 |
Chemical Properties | Back Directory | [Boiling point ]
617.4±55.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Cryst. | [pka]
14.20±0.20(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
Alisol F is a triterpene isolated from Alisma orinentale, has immunosuppressive and anti-virus functions. Alisol F exhibits inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the HepG2.2.15 cell line with an IC50 of 0.6 μM[1]. | [target]
NOS | NO | TNF-α | IL Receptor | COX | STAT | NF-kB | ERK | JNK | p38MAPK | HBV | [storage]
Store at -20°C | [References]
[1] Zhi-Yong Jiang, et al. A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis.Planta Med DOI:10.1055/s-2006-947178 |
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