| Identification | Back Directory | [Name]
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone | [CAS]
152831-00-0 | [Synonyms]
Benzbromarone Impurity 10
Benzbromarone 6-Hydroxy Impurity
Benzbromarone Impurity 7 (6-Hydroxy-Benzbromarone)
Benzbromarone Impurity 10 (6-Hydroxy-Benzbromarone）
(3,5-dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxybenzofuran-3-yl)methanone
METHANONE,(3,5-DIBROMO-4-HYDROXYPHENYL)(2-ETHYL-6-HYDROXY-3-BENZOFURANYL)- | [Molecular Formula]
C17H12Br2O4 | [MDL Number]
MFCD00869983 | [MOL File]
152831-00-0.mol | [Molecular Weight]
440.08 |
| Chemical Properties | Back Directory | [Boiling point ]
444.9±45.0 °C(Predicted) | [density ]
1.785±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
4.53±0.25(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
6-Hydroxybenzbromarone is an angiogenic agent with potent inhibitory effects on cell migration, tubulogenesis and angiogenesis. | [Biological Activity]
6-Hydroxybenzbromarone is the main metabolite of Benzbromarone, which has a longer half-life and greater pharmacological potency than the parent compound. 6-Hydroxybenzbromarone is an EYA3 inhibitor with IC50 of 21.5 μM. | [target]
IC50: 21.5 μM (EYA3); metabolite | [storage]
Store at -20°C |
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