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ChemicalBook--->CAS DataBase List--->1527517-50-5

1527517-50-5

1527517-50-5 Structure

1527517-50-5 Structure
IdentificationBack Directory
[Name]

c-Fms-IN-10
[CAS]

1527517-50-5
[Synonyms]

C-FMS-IN-10
c Fms IN 10,cFmsIN10
[Molecular Formula]

C22H19N7OS
[MDL Number]

MFCD32197247
[MOL File]

1527517-50-5.mol
[Molecular Weight]

429.5
Chemical PropertiesBack Directory
[Boiling point ]

632.5±55.0 °C(Predicted)
[density ]

1.50±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

10.99±0.43(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, an kinase inhibitor of FMS (Colony stimulating factor-1 receptor, CSF-1R) with IC50 of 2 nM.c-Fms-IN-10 has anti-tumor activity[1].

[References]

[1]. Kim YY, et al. Synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel FMS inhibitors. Bioorg Med Chem Lett. 2019 Jan 15;29(2):271-275.

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