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ChemicalBook--->CAS DataBase List--->152068-09-2

152068-09-2

152068-09-2 Structure

152068-09-2 Structure
IdentificationBack Directory
[Name]

YO-PRO 1
[CAS]

152068-09-2
[Synonyms]

Yo
YO-PRO 1
Yo-pro 1 iodide
Oxazole yellow, ≥99%
Oxazole yellow >=98% (HPLC)
Oxazole yellow, 1mM in DMSO
Quinolinium, 4-((3-methyl-2(3H)-benzoxazolylidene)methyl)-1-(3-(trimethylammonio)propyl)-, diiodide
[Molecular Formula]

C24H29IN3O+
[MOL File]

152068-09-2.mol
[Molecular Weight]

502.42
Chemical PropertiesBack Directory
[Melting point ]

>250 ℃
[storage temp. ]

2-8°C
[solubility ]

H2O: soluble5, clear (warmed)
[form ]

powder
[color ]

yellow to orange-brown
[biological source]

r at blood
[Water Solubility ]

H2O: 5, clear (warmed)
[λmax]

491 nm
[Biological Applications]

Nucleic acid hybridization; nucleic acid sequencing; detecting nucleic acids,cells,bacteria,immunodeficiency virus,microorganisms; counting embryoblasts,viruses; apoptosis assay; white blood cell functional assay
Safety DataBack Directory
[RIDADR ]

UN 2811 6.1 / PGIII
Hazard InformationBack Directory
[Uses]

Hybridisation and cloning studies
[Definition]

ChEBI: An unsymmetrical C1 cyanine dye having 1,3-benzoxazol-2-yl and quinolinium-4-yl substituents.
[Biochem/physiol Actions]

Oxazole yellow is a fluorescent cyanine dye that binds to DNA and is used to detect apoptotic cells. Oxazole yellow does not enter live cells. However, during apoptosis the cytoplasmic membrane becomes slightly permeable, allowing entry of the dye. Oxazole yellow is often used along with propidium iodide (catalog no. P4170), a DNA dead cell stain that does not enter either live or apoptotic cells. The λEx/λEm of Oxazole yellow is 491/509.
[storage]

-20°C (protect from light)
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