| Identification | Back Directory | [Name]
ZINQUIN ETHYL ESTER | [CAS]
151606-29-0 | [Synonyms]
ZINQUIN-E
Zinquin A
Zinquin Acid
ZINQUIN ETHYL ESTER
Zinquin >=95% (HPLC), solid
ETHYL(2-METHYL-8-P-TOLUENESULFONAMIDO-6-QUINOLYLOXY)ACETATE
2-((2-Methyl-8-(4-MethylphenylsulfonaMido)quinolin-6-yl)oxy)acetic acid
Ethyl[[2-mthyl-8-[[(4methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]acetate
2-Methyl-8-[(4-methylphenyl)-sulfonamido]-6-(ethoxycarbonylmethoxy)-quinoli
ETHYL [2-METHYL-8-[[(4-METHYLPHENYL)SULFONYL]AMINO]-6-QUINOLINYL]OXY ACETATE
2-METHYL-8-(4-METHYLPHENYLSULFONYLAMINO)QUINOLINYL]OXYACETIC ACID ETHYL ESTER
Acetic Acid, [[2-methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]-
2-METHYL-8-[(4-METHYLPHENYL)SULFONYLAMINO]-6-(ETHYLOXYCARBONYLMETHYLOXY)QUINOLINE
ETHYL[[2-METHYL-8-[[(4-METHYLPHENYL)SULFONYL]AMINO]-6-QUINOLINYL]OXY]ACETATE (ZINQUIN ETHYL ESTER) | [Molecular Formula]
C21H22N2O5S | [MDL Number]
MFCD00797629 | [MOL File]
151606-29-0.mol | [Molecular Weight]
414.47 |
| Chemical Properties | Back Directory | [Appearance]
White or Pale Blue Crystalline Solid | [Melting point ]
112-114°C | [Boiling point ]
608.0±65.0 °C(Predicted) | [density ]
1.412±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble | [form ]
crystals | [pka]
pK1 (quinoline nitrogen): <2; pK (carboxylic acid proton): 5.77 ±0.03; pK (sulfonamide proton): 9.91±0.02(at 25℃) | [color ]
off-white | [λmax]
368 nm | [Biological Applications]
Zinc indicator; detecting apoptosis |
| Hazard Information | Back Directory | [Chemical Properties]
White or Pale Blue Crystalline Solid | [Uses]
A fluorescent reagent and indicator of intracellular zinc ions. An analogue of widely used indicator, TS-Q. Zinquin ethyl ester is membrane permeable therefore useful to detect intracellular zinc ions. Zinquin ethyl ester forms a complex with a zin | [Biochem/physiol Actions]
Zinquin is a membrane-permeant fluorophore. It is used to detect zinc in cells by UV fluorescence. Zinquin ethyl ester can be used to monitor the change in intracellular concentrations of Zn2+ in thymocytes and hepatocytes. The ester is excited at 368nm and emits at 490nm. |
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