| Identification | Back Directory | [Name]
DMTr-dH2U-amidite | [CAS]
151503-28-5 | [Synonyms]
DMTr-dH2U-amidite
2-Deoxy-2’-deoxy-5’-(4,4’-dimethoxytrityl)uridine-3’-CED phosphoramidite
4(1H)-Pyrimidinone, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]- | [Molecular Formula]
C39H47N4O7P | [MDL Number]
MFCD34548973 | [MOL File]
151503-28-5.mol | [Molecular Weight]
714.79 |
| Hazard Information | Back Directory | [Uses]
DMTr-dH2U-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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