| Identification | Back Directory | [Name]
inokosterone | [CAS]
15130-85-5 | [Synonyms]
inokosterone
Lnokosterone
(22R)-2β,3β,14,20,22,26-Hexahydroxy-5β-cholest-7-en-6-one
Cholest-7-en-6-one, 2,3,14,20,22,26-hexahydroxy-, (2β,3β,5β,22R)-
5-beta-Cholest-7-en-6-one, 2-beta,3-beta,14,20,22,26-hexahydroxy-, (22R,25rs)-
Cholest-7-en-6-one, 2,3,14,20,22,26-hexahydroxy-, (2-beta,3-beta,5-beta,22R)- (9ci) | [Molecular Formula]
C27H44O7 | [MDL Number]
MFCD01745899 | [MOL File]
15130-85-5.mol | [Molecular Weight]
480.638 |
| Chemical Properties | Back Directory | [Melting point ]
255℃ (dec.) | [Boiling point ]
498.63°C (rough estimate) | [density ]
1.28±0.1 g/cm3 (20 ºC 760 Torr) | [refractive index ]
1.5800 (estimate) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
14.13±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Inokosterone is a potential agent target of estrogen receptor 1 in rheumatoid arthritis patients[1]. | [Definition]
ChEBI:Inokosterone is a 2beta-hydroxy steroid, a 3beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 20-hydroxy steroid, a 26-hydroxy steroid, a 6-oxo steroid, a 22-hydroxy steroid and a phytoecdysteroid. | [References]
[1] Mo JH, et al. Inokosterone Is A Potential Drug Target of Estrogen Receptor 1 in Rheumatoid Arthritis Patients: Analysis from Active Ingredient of Cyathula Officinalis.?Chin J Integr Med. 2021;27(10):767-773. DOI:10.1007/s11655-021-3492-5 |
|
|