| Identification | Back Directory | [Name]
5-Methoxycanthinone | [CAS]
15071-56-4 | [Synonyms]
Alkaloid PA-1
5-Methoxycanthinone
5-Methoxycanthin-6-one
5-Methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one,5-methoxy- | [Molecular Formula]
C15H10N2O2 | [MDL Number]
MFCD21333774 | [MOL File]
15071-56-4.mol | [Molecular Weight]
250.25 |
| Hazard Information | Back Directory | [Uses]
5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells[1][2]. | [Definition]
ChEBI: 5-Methoxycanthin-6-one is an alkaloid and an organic heterotetracyclic compound. | [IC 50]
Leishmania | [storage]
Store at -20°C | [References]
[1] Ferreira ME, et al. Leishmanicidal activity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum chiloperone var. angustifolium. J Ethnopharmacol. 2002 May;80(2-3):199-202. DOI:10.1016/s0378-8741(02)00025-9
[2] Anderson LA, et al. Production of cytotoxic canthin-6-one alkaloids by Ailanthus altissima plant cell cultures. J Nat Prod. 1983 May-Jun;46(3):374-8. DOI:10.1021/np50027a014 |
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