| Identification | Back Directory | [Name]
C10 bisphosphonate | [CAS]
15049-93-1 | [Synonyms]
C10 bisphosphonate
1-Aminodecylidene bis-Phosphonic Acid
Phosphonic acid, P,P'-(1-iminodecylidene)bis- | [Molecular Formula]
C10H25NO6P2 | [Molecular Weight]
317.26 |
| Chemical Properties | Back Directory | [Boiling point ]
537.8±60.0 °C(Predicted) | [density ]
1.346±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
A crystalline solid | [pka]
-0.58±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
1-Aminodecylidene bis-phosphonic acid is a potent inhibitor of acid sphingomyelinase (IC50 = 20 nM). It is selective for acid sphingomyelinase over neutral sphingomyelinase (IC50 = >100 μM). 1-Aminodecylidene bis-phosphonic acid completely inhibits apoptosis induced by dexamethasone in HepG2 cells. |
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| Company Name: |
Creative Enzymes
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1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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