Identification | Back Directory | [Name]
fura red | [CAS]
149732-62-7 | [Synonyms]
fura red Fura Red,AM Fura Red, AM *CAS 149732-62-7* Fura 2-TH, AM (Known as Fura Red(TM), TM of Molecular Probes) Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[5-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-2-[(5-oxo-2-thioxo-4-imidazolidinylidene)methyl]-6-benzofuranyl]-, (acetyloxy)methyl ester | [Molecular Formula]
C41H44N4O20S | [MOL File]
149732-62-7.mol | [Molecular Weight]
944.87 |
Hazard Information | Back Directory | [Uses]
Fura Red is a Ca2+-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca2+][1]. | [Definition]
ChEBI: A 1-benzofuran substituted at position 2 by a (5-oxo-2-thioxoimidazolidin-4-ylidene)methyl group, and at C-5 and C-6 by heavily substituted oxygen and nitrogen functionalities respectively. | [References]
[1] Floto RA, et al. IgG-induced Ca2+ oscillations in differentiated U937 cells; a study using laser scanning confocal microscopy and co-loaded fluo-3 and fura-red fluorescent probes. Cell Calcium. 1995 Nov;18(5):377-89. DOI:10.1016/0143-4160(95)90053-5 [2] Wendt ER, et al. Ratiometric analysis of fura red by flow cytometry: a technique for monitoring intracellular calcium flux in primary cell subsets. PLoS One. 2015 Apr 2;10(3):e0119532. DOI:10.1371/journal.pone.0119532 |
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