| Identification | Back Directory | [Name]
4-amidinoindan-1-one 2'-amidinohydrazone | [CAS]
149400-88-4 | [Synonyms]
SAM 486A
CGP 48664
SardoMozide
4-amidinoindan-1-one 2'-amidinohydrazone
(E)-2-(4-carbaMiMidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinec
2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide
(E)-2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide
Hydrazinecarboximidamide, 2-[4-(aminoiminomethyl)-2,3-dihydro-1H-inden-1-ylidene]- | [Molecular Formula]
C11H14N6 | [MDL Number]
MFCD00920906 | [MOL File]
149400-88-4.mol | [Molecular Weight]
230.27 |
| Chemical Properties | Back Directory | [Boiling point ]
438.8±55.0 °C(Predicted) | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Soluble in DMSO | [pka]
11.54±0.20(Predicted) |
| Hazard Information | Back Directory | [Biological Activity]
Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM. | [in vitro]
Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC 50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells. | [target]
| [storage]
Store at -20°C |
|
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Twochem Co.Ltd.
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021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
MedChemExpress
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021-58955995 |
| Website: |
www.medchemexpress.com |
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