Identification | Back Directory | [Name]
L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl- | [CAS]
147732-56-7 | [Synonyms]
Pal-AHK Pal-GHK-OH Collaxyl II Palmitoyl-GHK Pal-GHK, >=95% Pal-Tripeptide-1 Palm-Gly-His-Lys Peptides PAL-Ghk PAL-GLY-HIS-LYS-OH Palmiltoyl Tripepti Pal-GHK/Matrixyl 3000 PALMITOYL TRIPEPTIDE-1 PAL-GHK / palmitoyl-GHK PalMitoyl Tripeptide-1、3 Palmitoyl Tetrapeptide-1 Pal-GHK | Pal-Gly-His-Lys Palmitoyl Tripeptide-1Pal-AHK Palmitoyl Tripeptide-1/Pal-GHK Pal-GHK(PalMitoyl Tripeptide-1) Cosmetic peptide powder/Pal-AHK PAL-GHK (Palmitoyl-Oligopeptide) Palmiltoyl Tripeptide-1 (Pal-GHK) Palmitoyl Tripeptide-1, Bio-bustyl Material Pure Palmitoyl Tripeptide-1 N-Palmitoylglycyl-L-histidyl-L-lysine Peptide Palmitoyl Tripeptide-1 PAL-GHK N-(1-Oxohexadecyl)glycyl-L-histidyl-L-lysine N2-[(N-Palmitoylglycyl)-L-histidyl]-L-lysine Palmitoyl Tripeptide-1、Palmitoyl Oligopeptide N-1(1-oxohexadecyl-glycyl-L-histidyl-L-Lysine Matrixyl 3000 powder / Palmitoyl Tripeptide-1 L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl- Palmitoyl Tripeptide-1 / Pal-GHK/Matrixyl 3000 Matrixyl 3000 / Pal-GHK/ Palmitoyl Tripeptide-1 Cosmetic Raw Material Pure Palmitoyl Tripeptide-1 Collaxyl II / Palmitoyl tripeptide-1, Biopeptide CL Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7 N2-[N-[N-(1-oxohexadecyl)glycyl]-L-histidyl]-L-lysine Cosmetic Peptides Palmitoyl Tripeptide-1 Anti-Wrinkle N-1(1-oxohexadecyl-glycyl-L-histidyl-L-Lysine USP/EP/BP Peptide Palmitoyl Tripeptide-1 (PAL-GHK / palmitoyl-GHK) China biggest manufacturer, Palmitoyl Tripeptide,147732-56-7 Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7 USP/EP/BP Palmitoyl Tripeptide-3 (Pal-AHK)Palmitoyl Tripeptide-3 (Pal-AHK) Palmitoyl Tripeptide-1 (PalGHK)Palmitoyl Tripeptide-1 (PalGHK) superior quality N-1(1-oxohexadecyl-glycyl-L-histidyl-L-Lysine CAS 147732-56-7 (S)-2-((S)-3-(1H-Imidazol-5-yl)-2-(2-palmitamidoacetamido)propanamido)-6-aminohexanoic acid | [EINECS(EC#)]
-0 | [Molecular Formula]
C30H54N6O5 | [MDL Number]
MFCD18251733 | [MOL File]
147732-56-7.mol | [Molecular Weight]
578.79 |
Chemical Properties | Back Directory | [Boiling point ]
913.0±65.0 °C(Predicted) | [density ]
1.105 | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 30 mg/ml | [form ]
A solid | [pka]
3.16±0.10(Predicted) | [Sequence]
Pal-Gly-His-Lys | [InChIKey]
BYUQATUKPXLFLZ-UIOOFZCWSA-N | [SMILES]
C(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)CCCCCCCCCCCCCCC |
Hazard Information | Back Directory | [Description]
A peptide is two or more amino acids joined together and is the building block of protein. Peptides fall into three main categories: signal peptides, carrier peptides, and those that inhibit nerve signals. Signal peptides, like palmitoyl tripeptide-1, act as messengers to cells, which trigger collagen synthesis, which then increases skin firmness.Palmitoyl tripeptide-1 is a small three amino acid signal peptide with the amino sequence of glycine-histidine-lysine (GHK). GHK is attached to palmitic acid (a fatty acid) to increase its skin penetration and oil solubility. | [Uses]
Palmitoyl Tripeptide-1, has shown to have effects on on collagen, fibronectin, hyaluronic acid synthesis in human dermal fibroblasts, and thus can be used in preparation of antiaging cosmetic creams. | [Application]
Palmitoyl Tripeptide-1 (Pal-GHK, SpecPed? PT1P) is useful in anti-aging products and wrinkle treatment products such as gels, serums, lotions and creams. Acting as messengers of cutaneous restructuration and repair, this peptide works synergistically to restore and maintain the skin's youthful appearance. | [Clinical Use]
Applying palmitoyl tripeptide-1 directly to your skin tells the cells to make more collagen, stimulating new collagen production. It requires at least one month or more to begin to see visible changes from new collagen with maximum results visible after 3 to 4 months. Erin Gilbert, MD, FAAD, Ph.D., and board-certified dermatologist and neuroscientist, continues: "Peptides can be included in serums, moisturizers, and masks," Gilbert explains. "They are also included in some topical serums used after micro-needling or superficial laser procedures to increase the penetration of the peptide and help the skin recover from the procedure." | [Safety]
The CIR Expert Panel concluded that peptides, such as palmitoyl tripeptide-1, are safe in cosmetics and self-care products. Environmental Working Group (EWG) currently scores palmitoyl tripeptide-1 as “1” or “l(fā)ow hazard.”O(jiān)verall, peptides, such as palmitoyl tripeptide-1, mimic what already exists in the human body and research on peptides’ impact on the skin shows limited to no skin irritation. In terms of toxicity caused by peptides, there is no published research to document any known toxicity. |
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