| Identification | Back Directory | [Name]
4-Amino-2-trifluoromethylpyridine | [CAS]
147149-98-2 | [Synonyms]
Enasidenib Intermediate 4
2-trifluoromethyl-4-aminopyridine
2-(trifluoromethyl)pyridin-4-amin
2-(Trifluoromethyl)-4-pyridinamine
2-Ctrifluoromethyl/pyridin-4-amine
2-(Trifluoromethyl)pyridin-4-amine
2-Trifluoromethyl-pyridin-4-ylamine
4-Amino-2-(trifluoromethyl)-pyridine
4-Pyridinamine, 2-(trifluoromethyl)-
2-CTRIFLUOROMETHYL/PYRIDIN-4-AMINE,98%
4-Amino-2-(trifluoromethyl)pyridine HCl
CAS:147149-98-2 4-Amino-2-trifluoromethylpyridine
4-Amino-2-trifluoromethylpyridine ISO 9001：2015 REACH
2-(Trifluoromethyl)pyridin-4-amine (4-Amino-2-trifluoromethylpyridine) | [Molecular Formula]
C6H5F3N2 | [MDL Number]
MFCD09056877 | [MOL File]
147149-98-2.mol | [Molecular Weight]
162.12 |
| Chemical Properties | Back Directory | [Melting point ]
58-62°C | [Boiling point ]
230.7±40.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
powder to crystal | [pka]
4.62±0.50(Predicted) | [color ]
White to Almost white |
| Hazard Information | Back Directory | [Chemical Properties]
4-Amino-2-trifluoromethylpyridine can undergo a Chichibabin reaction to introduce an additional amine group in the para-position. It is employed in the synthesis of oral checkpoint kinase inhibitor for immunotherapy. | [Uses]
4-Amino-2-(trifluoromethyl)pyridine are involved in many syntheses of active pharmaceutical ingredients (APIs), such as naporafenib, a RAF inhibitor used in the treatment of RAF-driven cancers. |
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