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ChemicalBook--->CAS DataBase List--->1466427-02-0

1466427-02-0

1466427-02-0 Structure

1466427-02-0 Structure
IdentificationBack Directory
[Name]

Endothelial lipase inhibitor-1
[CAS]

1466427-02-0
[Synonyms]

Endothelial lipase inhibitor-1
[Molecular Formula]

C22H22N4O4
[MOL File]

1466427-02-0.mol
[Molecular Weight]

406.43
Chemical PropertiesBack Directory
[density ]

1.39±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 25 mg/mL (61.51 mM; Need ultrasonic)
[form ]

Solid
[pka]

6.07±0.10(Predicted)
[color ]

Off-white to gray
Hazard InformationBack Directory
[Biological Activity]

Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM.
[storage]

Store at -20°C
[References]

[1]. Hu CH, et al. Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3721-3725.
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