| Identification | Back Directory | [Name]
L-692,585 | [CAS]
145455-35-2 | [Synonyms]
L-692
L-692,585
3-[[(2R)-2-hydroxypropyl]amino]-3-methyl-N-[(3R)-2-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-4,5-dihydro-3H-1-benzazepin-3-yl]butanamide
3-[[(2R)-2-Hydroxypropyl]amino]-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]-butanamide
Butanamide, 3-[[(2R)-2-hydroxypropyl]amino]-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]- | [Molecular Formula]
C32H37N7O3 | [MDL Number]
MFCD00915396 | [MOL File]
145455-35-2.mol | [Molecular Weight]
567.68 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at -20°C | [solubility ]
Soluble to 100 mM in DMSO and to 25 mM in ethanol | [form ]
Powder | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
L-692,585 shows potent and selective GH-secretory activity in several species including human. | [Definition]
ChEBI: 3-[[(2R)-2-hydroxypropyl]amino]-3-methyl-N-[(3R)-2-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-4,5-dihydro-3H-1-benzazepin-3-yl]butanamide is a peptide. | [Biological Activity]
Highly potent, non-peptide ghrelin receptor (GHS-R1a) agonist (K i = 0.8 nM). Increases plasma GH levels in vivo and is 2- to 2.5-fold more potent than GHRP-6. | [storage]
Desiccate at -20°C |
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